Since the early 1990s, when climate change issues rose, the EU and its Member-States have introduced ambitious objectives and policies related to climate change adaptation, which directly affected its Member- States' climate policy framework. However, many policies concerning climate change adaptation have either direct spatial reference or significant spatial effects. Therefore, the analysis between the Regional Adaptation Action Plans and other types of regional-scaled plans, such as the Regional Spatial Planning Frameworks, is regarded to be valuable. This paper examines the compatibility and complementarity of objectives, measures and tools between the Regional Adaptation Action Plan and the Regional Spatial Planning Framework of South Aegean. The analysis performed revealed linkages between the RAAP and the RSPF of the South Aegean in terms of objectives, measures and tools.