The marine environment is the final recipient and digester of litter. Floating and benthic litter constitute the majority of litter items in the marine environment while both remain quite unexploited due to their demand in high-cost and time-consuming surveys. In this paper we propose an integrated approach for assessing in detail the spatial distribution and composition of benthic litter in coastal environments, through the use of underwater towed cameras. The method is showcased in Syros Island, Cyclades, Greece where benthic litter density maps revealed benthic litter sources and environmental drivers controlling their spatial distribution and general pathways.