In this study total Cr, Cr(VI), Ni, major and some trace elements were determined in groundwater of northern sector of the Pollino Massif. The investigated area is characterized by ophiolitic rocks consisting of metabasites and cataclastic and highly fractured serpentinites. Two different hydro-facies were observed, reflecting low-temperature water-rock interactions. The Mg-HCO3 hydrofacies was determined through the weathering of serpentinites, the Ca-HCO3 groundwater are due to the interaction with calcschist and metabasites. High Cr(VI) concentrations were detected, exceeding the maximum admissible concentrations by Italian regulation, due to the release of Cr(III) from ophiolitic rocks into water and its oxidation to the hexavalent state. Remediation tests were performed at different liquid/solid concentration, and the kinetic data were interpreted with a suitable mathematical model.